Researcher

Li Li

Jiangnan University

2 developments in the corpus

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SEP 3, 2026 · JOURNAL ARTICLE

Functional coupling between MC4R and Kir7.1 contributes to clozapine-induced weight gain in female mice

Nature Communications

Mechanistic study in a mouse model proposing a novel signaling pathway for clozapine-induced weight gain, without evidence of clinical translation or validation in humans.

Hypothesis-GeneratingBaijie Xu Luis E. Gimenez Neurotransmitter Receptor Influence on Behavior

Study details

DesignExperimental animal model study with geneti…

InterventionClozapine administration; genetic deletion…

ComparatorVehicle or wild-type control; antipsychotic…

AUG 11, 2026 · JOURNAL ARTICLE

Dynamic Responses of α-Amylase to Dietsand Their Impact on Metabolic Health: Insights from a Novel NoninvasiveImaging

Journal of Agricultural and Food Chemistry

Early-phase preclinical study demonstrating a novel imaging probe in mice with exploratory findings on diet-enzyme relationships; lacks human validation, clinical endpoints, and comparative controls.

PreliminaryJuncai Leng Li Li Beibei Wang

Reported

Time to peak α-amylase activity a…2 h