Drug Delivery

OCT 19, 2026 · JOURNAL ARTICLE

Microneedle-based drug delivery for inflammatory and immune-mediated ocular diseases: current applications and future perspectives.

Drug Delivery

Inflammatory and immune-mediated ocular diseases encompass a spectrum of conditions that arise from dysregulated immune-inflammatory responses marked by a chronic clinical course,

OCT 15, 2026 · JOURNAL ARTICLE

Overcoming the nuclear barrier in nonviral gene therapy: mechanisms, carrier design, and translational perspectives on NLS peptide and DNA targeting sequence strategies.

Drug Delivery

Efficient delivery of plasmid DNA (pDNA) into the nucleus remains a major bottleneck in nonviral gene therapy, particularly in post-mitotic and slowly dividing cells where the nucl

AUG 12, 2026 · JOURNAL ARTICLE

Targeted delivery of mRNA to immune cells for in vivo cell therapy.

Drug Delivery

A comprehensive review article synthesizing current knowledge on mRNA delivery engineering strategies to immune cells, identifying translational barriers and technical advances rather than reporting original experimental results or clinical outcomes.

AUG 12, 2026 · JOURNAL ARTICLE

Artificial intelligence and extracellular vesicles in oncology: towards tumor diagnosis, prediction, and therapy.

Drug Delivery

This is a narrative review synthesizing emerging applications of AI in extracellular vesicle research; it raises mechanistic and translational questions rather than reporting original empirical results or clinical outcomes.

AUG 5, 2026 · JOURNAL ARTICLE

Comparative safety profiles of antibody-drug conjugates: a real-world analysis of monotherapy and combination regimens in solid tumors.

Drug Delivery

Large real-world pharmacovigilance study of 19,697 adverse event reports confirms known structure-toxicity relationships for ADCs, but lacks comparative efficacy data and uses observational methods without prospective controls.

MAY 27, 2026 · JOURNAL ARTICLE

Lysosome-directed targeted protein degradation technologies for overcoming cancer drug resistance: mechanisms, design principles, and therapeutic opportunities.

Drug Delivery

A comprehensive review article synthesizing mechanistic principles and design strategies for an emerging therapeutic modality (LYTACs) in preclinical and early translational stages, with no primary experimental data or clinical trial results.