Liver Disease Diagnosis and Treatment / Diabetes, Cardiovascular Risks, and Lipoproteins · Journal article
Healthcare · August 17, 2026
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This qualitative interview study of 25 adults with MASLD identified five key themes: communication and emotions at diagnosis, independent information seeking, post-diagnosis lived experiences, support needs, and future disease progression concerns. The findings underscore gaps in patient education, diagnosis clarity, and follow-up support, with participants expressing anxiety about disease progression and requesting enhanced information and healthcare follow-up.
Qualitative interview study with reflexive thematic analysis. Adults living with MASLD; age range 24–79 years; 40% male; setting and eligibility criteria not specified.. Intervention: Semi-structured interview on diagnosis and lived experiences with MASLD. n = 25.
25 adults with MASLD interviewed (age range 24–79 years; 40% men) Many participants received diagnosis incidentally with lack of clarity at point of diagnosis Concerns included internet-sourced information, symptoms, social relationships, stigma, and lifestyle modification
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Clinicians should recognize that MASLD patients often receive incidental diagnoses with insufficient explanation, and report significant unmet needs for education, clarity on disease progression risk, and structured follow-up. These findings suggest opportunities to improve patient communication and support at the point of diagnosis and during ongoing care.
A small qualitative study with 25 participants exploring lived experience and support needs; generates themes for future intervention design but does not test clinical outcomes or interventions.
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Quoted from the source exactly as published.
Clinicians should recognize that MASLD patients often receive incidental diagnoses with insufficient explanation, and report significant unmet needs for education, clarity on disease progression risk, and structured follow-up. These findings suggest opportunities to improve patient communication and support at the point of diagnosis and during ongoing care.
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Background/Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is caused by excessive fat accumulation in the liver (steatosis) and affects approximately 38% of adults globally. MASLD may progress from simple steatosis to fibrosis and cirrhosis and is closely related to other cardio-metabolic conditions (e.g., obesity and type 2 diabetes), posing a risk factor for cardiovascular disease. Currently, lifestyle modification and weight reduction remain the main initial treatment options. Existing data suggest that there is low awareness among patients regarding MASLD diagnosis and its subsequent management. Therefore, this study aimed to develop a rich understanding of the lived experiences, concerns, and support needs of adults with MASLD. Methods: A qualitative design was applied, utilizing semi-structured interviews. Adults living with MASLD were invited to talk about their diagnosis and discuss their lived experiences. Participants were interviewed by telephone or video call, and each interview was transcribed and analyzed with a reflexive thematic analysis approach. Results: Twenty-five adults with MASLD (age range: 24–79 years; 40% men) were interviewed. The emergent key themes related to communication and emotions at diagnosis; independently seeking further information; lived experiences post-diagnosis; support needs; and future concerns. Many participants reported receiving the diagnosis incidentally, and a number of issues were raised regarding lack of clarity at the point of diagnosis. Additional concerns included information obtainable via the internet, symptoms, social relationships, stigma, and lifestyle modification. Future anxieties related mainly to fears of disease progression, while support needs were predominantly focused on information and follow-up. Conclusions: The concerns and support needs identified by this study highlight key issues/themes that should inform education and support initiatives by relevant healthcare services aiming to improve the lived experiences and holistic management of adults with MASLD.
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