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Marital Conflict / Cognitive Behavioral Therapy / Anxiety · Interventional Study
ClinicalTrials.gov · September 8, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a planned three-arm RCT comparing Acceptance and Commitment Therapy, Cognitive Behavioral Therapy, and treatment-as-usual for major depressive disorder in the context of marital crisis. No results have been posted to the registry; the study has not yet begun recruitment. The trial design incorporates appropriate blinding and multiple follow-up time points but is at present only a protocol registration.
Interventional, Randomized, Parallel, Double masking, Treatment purpose. Depression - Major Depressive Disorder, Anxiety, Marital Conflict; age from 20 Years; to 60 Years. Intervention: Acceptance and commitment therapy. Compared with: Cognitive behavioral therapy — Active Comparator; Treatment-As-Usual Control Group — No Intervention. n = 120. 1 site: China.
This is a planned three-arm RCT comparing Acceptance and Commitment Therapy, Cognitive Behavioral Therapy, and treatment-as-usual for major depressive disorder in the context of marital crisis. No results have been posted to the registry; the study has not yet begun recruitment. The trial design incorporates appropriate blinding and multiple follow-up time points but is at present only a protocol registration.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
This is a planned RCT registration with no results reported; the study is not yet recruiting and carries the design elements of a rigorous trial but no outcome data to evaluate.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07808021). This is a study registration, not published results. Lead sponsor: Universiti Sains Malaysia. Recruitment status: NOT_YET_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 120 participants (ESTIMATED). Conditions: Depression - Major Depressive Disorder, Anxiety, Marital Conflict. Interventions: BEHAVIORAL: Acceptance and Commitment Therapy; BEHAVIORAL: Cognitive Behavioral Therapy. Primary outcome measures: Severity of depressive symptoms assessed by Beck Depression Inventory-II , Change of the BDI-II score from baseline, 8 weeks at completion of intervention, 12 weeks after completion of intervention and 24 weeks after completion of intervention. Brief summary: This parallel three-arm, single-blind (assessor-blinded), randomized controlled trial (RCT) aims to compare the effects of ACT, CBT, and treatment-as-usual (TAU) on the severity of depressive symptoms (primary outcome), the severity of comorbid anxiety symptoms, marital satisfaction, intimacy with spouse, quality of life, and experiential avoidance (secondary outcomes) among people diagnosed with major depressive disorder (MDD) with marital crisis across four time points (T0 = baseline (pre-intervention), T1 = post-intervention (immediately after completion of the intervention, 8 weeks after its commencement), T2 = follow-up at 12 weeks after completion of the intervention, T3 = follow-up at 24 weeks after completion of the intervention). A total of 120 MDD patients with marital crisis will be recruited from two study sites and randomized by stratified block randomization into three groups (ACT, CBT and TAU) in a 1:1:1 ratio. ACT group therapy will be conducted once a week for 8 weeks in the ACT group, while CBT group therapy once a week for 8 weeks will be carried out in the CBT group. During baseline assessment (T0), the demographic and clinical characteristics, the Chinese versions of the Beck Depression Inventory-II (BDI-II), the Generalized Anxiety Disorder 7-item scale (GAD-7), the Personal Assessment of Intimacy in Relationships (PAIR), the Dyadic Adjustment Scale (DAS), the World Health Organization Quality of Life-BREF (WHOQOL-BREF), and the Acceptance and Action Questionnaire-II (AAQ-II) will be administered to all participants. The re-administration of the BDI-II, GAD-7, PAIR, DAS, WHOQOL-BREF and AAQ-II will be carried out at T1, T2, and T3.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.