Depression Disorders / Depression Major Depressive Disorder / MediNF · Interventional Study

Meditative Neurofeedback for Depression

ClinicalTrials.gov · September 10, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a prospective registry record for an ongoing interventional study evaluating meditative neurofeedback for major depressive disorder. No results are reported in this registry entry, and the study remains in recruitment phase with an estimated small enrollment. Readers should await published results before drawing clinical conclusions.

What was studied

Interventional, Single Group, Open label, Treatment purpose. Depression - Major Depressive Disorder, Depression Disorders; age from 18 Years. Intervention: MediNF. n = 27. 1 site: United States.

Key findings

Safety

No secondary outcomes, safety measures, or follow-up duration beyond 8 weeks are described in this registry entry.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is an unstarted interventional study with no results reported; it is a prospective registry record describing a planned behavioral intervention for depression with a small estimated enrollment and surrogate outcome measure.

Study design

As stated by the source record.

MethodsPrimary outcome measure: PHQ9 (assessed at 8 weeks)

DesignInterventional, Single Group, Open label, Treatment purpose

PopulationDepression - Major Depressive Disorder, Depression Disorders; age from 18 Years

Sample size27

InterventionMediNF

Setting1 site: United States

Reported figures

Quoted from the source exactly as published.

Estimated enrollment27

Primary outcome measurePHQ9

Primary outcome timepoint8 weeks

Caveats

This is a registry record only; no results are reported or available.
Study phase is listed as NA; study design details (e.g., randomization, blinding, comparator arm) are not specified in this record.
Sample size is small (n=27 estimated); generalizability will be limited.
No secondary outcomes, safety measures, or follow-up duration beyond 8 weeks are described in this registry entry.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

limited

Interventional behavioral study; phase not specified; no comparator arm described in registry record.

Directness

moderate

PHQ9 is a validated depression symptom scale; directness depends on whether clinical outcomes will be assessed.

Consistency

insufficient

Registry record contains no results; consistency cannot be assessed.

Risk of bias

insufficient

No methodological details on blinding, allocation, or conduct are provided in this registration.

Sample adequacy

limited

Estimated enrollment 27 participants; small sample size limits generalizability and power.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT06675240). This is a study registration, not published results. Lead sponsor: University of California, San Diego. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 27 participants (ESTIMATED). Conditions: Depression - Major Depressive Disorder, Depression Disorders. Interventions: BEHAVIORAL: MediNF. Primary outcome measures: PHQ9 , 8 weeks. Brief summary: The goal of this study is to test a meditative neurofeedback intervention for depressed mood.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

Depression DisordersDepression Major Depressive DisorderNCT06675240University of California, San DiegoMediNF