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Large prospective population-based study with 339,435 mother-child pairs using validated exposure assessment and quantile g-computation to evaluate PM2.5 constituents and childhood obesity, showing consistent dose-response associations across multiple pollutants with narrow confidence intervals.
A single case report with no comparator, describing anecdotal response to a novel drug combination in an unusual population; insufficient to change practice or confirm efficacy.
Secondary analysis of an RCT with sound design showing significant improvements in self-care and task execution ability over 3 months, but limited by surrogate behavioral endpoints, single-centre recruitment, and unclear sample size reporting.
This is a narrative review of an emerging nanotechnology platform with preclinical mechanistic concepts and no clinical trial data, raising therapeutic possibilities rather than testing them in humans.