Following this puts new work involving it at the top of your briefing, with a note saying why it is there. Links are taken from the source record, never inferred.
American Journal of Physiology-regulatory, Integrative and Comparative Physiology
Preclinical animal study testing a combination intervention hypothesis with negative primary outcome; results do not support additive benefit and require clinical translation.
A sound but limited randomized controlled trial with a small sample showing a plausible metabolic benefit via redistribution of fat rather than weight loss, requiring confirmation in larger studies.
Small single-centre case-control observational study with culture-based microbial characterization and cross-sectional hormonal measurement; demonstrates associations but lacks experimental design, mechanistic validation, and generalizability to support clinical intervention.
An exploratory mechanistic study in rats using intracerebroventricular infusion; shows diet-dependent effects on hypothalamic neuropeptide expression and circulating hormones, but no behavioural or body weight change over 7 days, limiting evidence of clinical relevance.
A narrative review synthesizing mechanistic and in vitro evidence on phytochemicals and irisin as potential regulators of adipose tissue browning; raises a therapeutic strategy hypothesis but does not report clinical trial data or human efficacy outcomes.
A narrative review synthesizing existing evidence to propose a mechanistic explanation for obesity via evolutionary mismatch; raises a conceptual framework rather than presenting new empirical results or clinical trials.
A controlled animal study with multiple metabolic endpoints showing that time-restricted feeding improves hormone profiles and energy metabolism in a genetic knockout model, but lacks direct clinical translatability and relies on surrogate outcomes.
A narrative review synthesising current understanding of obesity management across non-pharmacological, herbal, approved pharmacological and emerging therapeutic strategies, without presenting new primary data or systematic evidence synthesis.