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Yang Chen

The University of Queensland

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SEP 8, 2026 · JOURNAL ARTICLE

Time-restricted feeding improved metabolic hormone levels and energy metabolism in high-fat diet-fed Leap2 -/- Mice

Journal of Endocrinology

A controlled animal study with multiple metabolic endpoints showing that time-restricted feeding improves hormone profiles and energy metabolism in a genetic knockout model, but lacks direct clinical translatability and relies on surrogate outcomes.

PromisingYueli Pu Chen Chen Yang Chen

Reported

Study duration10 weeks

Leap2+/+ normal diet sample size6

Leap2+/+ high-fat diet sample size6

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