Photodynamic Therapy Research Studies

SEP 11, 2026 · JOURNAL ARTICLE

A novel multi-functional FeZnCuInS/ZnS-TPPS4 conjugates as a promising theragnostic tool for combined photodynamic and photothermal therapy applications

Next Materials

In vitro proof-of-concept study of a novel nanomaterial showing biocompatibility and physical properties favourable for dual PDT/PTT, but no efficacy data, no in vivo work, and no comparison to standard therapies.

SEP 9, 2026 · JOURNAL ARTICLE

AR/PARP Dual‐Targeting Bioactive Photosensitizer for Photo‐Immunotherapy of Prostate Cancer

Advanced Materials

This is an early-stage mechanistic study describing synthesis and proposed mechanism of a novel photosensitizer in prostate cancer, without clinical data or in vivo efficacy results reported.

SEP 8, 2026 · JOURNAL ARTICLE

Rational Design of a Smart Phototheranostic Nanoagent Based on a NIR-II-Conjugated Polymer for Highly Tumor-Specific Multimodal Imaging-Guided Synergistic Therapy

Acs Applied Materials & Interfaces

This is a preclinical materials science study reporting rational design and in vitro/in vivo characterization of a nanoagent; it raises mechanistic questions about nanoparticle performance but does not test efficacy against a comparator in any clinical or disease model.

SEP 7, 2026 · JOURNAL ARTICLE

Immunogenic and systemic antitumor responses induced by photodynamic therapy: a systematic review of the abscopal effect

Cancer Cell International

This systematic review of preclinical animal models raises mechanistic questions about PDT's potential to trigger systemic immunity but does not provide clinical evidence sufficient to guide practice or confirm efficacy in humans.

SEP 5, 2026 · JOURNAL ARTICLE

Efficacy and Safety of DVDMS ‐Photodynamic Therapy for Dysphagia in Advanced Esophageal Cancer: A Phase II Clinical Trial

Cancer Science

Phase II trial with modest sample size showing acceptable safety profile and 40% response rate for dysphagia in advanced esophageal cancer, but requires larger confirmatory studies before clinical adoption.

SEP 4, 2026 · JOURNAL ARTICLE

Rational Design of Biocompatible Heavy-Atom-Free Thionaphthalimide-Based Nanophotosensitizers for Photodynamic Cancer Therapy

Acs Applied Bio Materials

Early-phase in vitro study of a novel photosensitizer design with cell-line validation but no in vivo efficacy, animal models, or clinical data.

AUG 18, 2026 · JOURNAL ARTICLE

Bio-adhesive cationic carbon dots enable photodynamic reactive oxygen species generation for cariogenic biofilm suppression

Materials Today Bio

Sound preclinical study with in vitro biofilm efficacy and in vivo proof-of-concept in a rat caries model, but limited to animal data and lacks human clinical validation.

AUG 14, 2026 · JOURNAL ARTICLE

Regulating Triplet Energy Level and Intramolecular Motion: An Aggregation-Induced Emission BODIPY for Near-Infrared Type I Photodynamic/Photothermal Synergistic Therapy

Acs Applied Materials & Interfaces

This is a proof-of-concept study of a novel photosensitizer design in a single tumor model with intratumoral dosing and short-term follow-up, demonstrating feasibility but lacking comparator arms, efficacy benchmarking, or systemic biodistribution data needed to establish clinical potential.