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Xue Chen

Southeast University

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AUG 14, 2026 · JOURNAL ARTICLE

Regulating Triplet Energy Level and Intramolecular Motion: An Aggregation-Induced Emission BODIPY for Near-Infrared Type I Photodynamic/Photothermal Synergistic Therapy

Acs Applied Materials & Interfaces

This is a proof-of-concept study of a novel photosensitizer design in a single tumor model with intratumoral dosing and short-term follow-up, demonstrating feasibility but lacking comparator arms, efficacy benchmarking, or systemic biodistribution data needed to establish clinical potential.

PreliminaryXue Chen Li Yang Yuanhang Li

Reported

Calculated T1 → S0 energy0.42 eV

Photothermal conversion efficiency54.44%

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