AUG 11, 2026 · JOURNAL ARTICLE
Effects of Chaihu-Shugan-San as an adjunctive intervention on psychosocial adaptation and meaning in life in patients with hepatocellular carcinoma comorbid with depression: a randomized controlled trial
Psycho-oncologie
Adequately powered, double-blind RCT with validated outcome measures in a defined population, but limited to surrogate psychosocial endpoints and a single centre context without separate reporting of effect sizes or confidence intervals.
Reported
Sample size randomized132
Sample size completed123
Baseline depression severity (HAM…≥17