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Zhentao Hou

First Hospital of Jiaxing

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SEP 5, 2026 · JOURNAL ARTICLE

Keratin conversion signature (KRT13/KRT4) defines a high-risk pancreatic cancer subtype with extensive malignant phenotypes

Discover Oncology

A novel biomarker derived from retrospective cohort data with validation in two independent datasets, showing consistent association with overall survival in pancreatic cancer, but lacking mechanistic validation or clinical intervention trials to establish actionability.

PromisingChen Gao Cancer and Skin Lesions Zhentao Hou

Reported

Discovery cohort sample size62

TCGA-PAAD validation cohort sampl…183

GEO validation cohort sample size289

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