Immune Cells in Cancer

SEP 8, 2026 · JOURNAL ARTICLE

Transmembrane lectins in cancer immunity: emerging drivers of myeloid-mediated immunosuppression

Frontiers in Immunology

A narrative review synthesizing mechanistic concepts and therapeutic potential of lectin–glycan interactions in cancer immunity, raising questions rather than reporting empirical results or clinical outcomes.

SEP 8, 2026 · JOURNAL ARTICLE

CAF-mediated immune exclusion in osteosarcoma: mechanisms, translational vulnerabilities, and therapeutic strategies

Journal of Translational Medicine

This is a narrative review synthesizing mechanistic and preclinical evidence on CAF biology in osteosarcoma, proposing translational directions without clinical trial data or validated biomarkers.

SEP 8, 2026 · JOURNAL ARTICLE

Extracellular Matrix Remodeling in Tumors: Forces Beyond Fibroblasts

Cancer Research

A narrative review article proposing a conceptual framework that challenges the fibroblast-centric model of ECM remodeling; raises questions about non-fibroblast stromal contributions rather than testing or confirming a specific empirical claim.

SEP 8, 2026 · JOURNAL ARTICLE

Tertiary lymphoid structures in urothelial carcinoma: bridging spatial architecture with therapeutic vulnerability in the post-BCG era

Frontiers in Immunology

A narrative review synthesizing current evidence and raising mechanistic questions about tertiary lymphoid structures in urothelial carcinoma, without new empirical data or prospective validation of proposed biomarker relationships.

SEP 8, 2026 · JOURNAL ARTICLE

Effects of Lactylation in Cancer Progression

Theoretical and Natural Science

A narrative review of mechanistic pathways linking protein lactylation to cancer phenotypes; raises questions about therapeutic potential but reports no empirical data, effect sizes, or clinical outcomes.

SEP 7, 2026 · JOURNAL ARTICLE

Immune cell-derived exosomes in cancer: double-edged mechanisms of antitumor immunity and tumor progression

Frontiers in Immunology

This is a narrative review synthesizing mechanistic literature on immune cell-derived exosomes in cancer, raising questions about bidirectional regulation rather than reporting new empirical data or clinical outcomes.

SEP 7, 2026 · JOURNAL ARTICLE

Beyond mismatch repair in colorectal cancer liver metastases: rethinking immunotherapy through the hepatic metastatic niche

Frontiers in Immunology

This is a conceptual framework paper proposing mechanistic hypotheses about hepatic disease as a modifier of immunotherapy efficacy in colorectal cancer, without new primary data or definitive evidence.

SEP 5, 2026 · JOURNAL ARTICLE

A CD44-targeted PDA/ZnO redox-active nanocomposite that couples chemotherapy with mitochondrial stress and tumor immune remodeling

Journal of Nanobiotechnology

Early-stage in vivo proof-of-concept in a single model system with no control arm comparison, surrogate endpoints, and no clinical translation data reported.