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André Konski

Chester County Hospital

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AUG 13, 2026 · JOURNAL ARTICLE

Stereotactic Body Radiotherapy vs Moderately Hypofractionated IMRT for Localized Intermediate-Risk Prostate Cancer

JAMA

Phase 3 randomized controlled trial with adequate sample size and median 3.2-year follow-up showing SBRT improved bowel quality of life and reduced high-grade genitourinary toxicity, but had lower disease-free survival than MH-IMRT.

Strong EvidenceProstate Cancer Treatment and Research Rodney J. Ellis Prostate Cancer Diagnosis and Treatment

Reported

Sample size698

SBRT dose36.25 Gy in 5 fractions

MH-IMRT dose70 Gy in 28 fractions or 60 Gy in 20 fracti…

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