Drug or technology

Vaccines, Attenuated

2 developments in the corpus

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AUG 7, 2026 · JOURNAL ARTICLE

Live-attenuated Toxoplasma gondii RHΔddx6 mutant establishes comprehensive immunity against acute, chronic, and congenital toxoplasmosis.

Virulence

A single-center preclinical study in mice showing robust immunogenicity and protection against multiple T. gondii challenge forms, but lacking human data and requiring further development before clinical translation.

PromisingYouke Fan Dead-box RNA Helicases Chronic Disease

Reported

Vaccine dose1 × 10^6 Δddx6 tachyzoites

Survival rate (lethal RH challeng…100%

Reduction in brain cyst burden (P…99.5%

JUN 11, 2026 · JOURNAL ARTICLE

Nanomaterial-based vaccines: An advanced approach against rotavirus: A review article.

Human Vaccines & Immunotherapeutics

This is a narrative review proposing nanomaterial-based vaccines as a solution to rotavirus vaccine efficacy gaps in LMICs, without presenting original experimental data or clinical trial results.

Hypothesis-GeneratingNanoparticles Ali Teimoori Kurosh Kalantar

Reported

Vaccine effectiveness in high-inc…80–90%

Vaccine effectiveness in low- and…40–70%