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This is a study protocol describing planned mixed-methods research; no results or data are reported, only the design and methodology for a future comparative study.
A single-center preclinical study in mice showing robust immunogenicity and protection against multiple T. gondii challenge forms, but lacking human data and requiring further development before clinical translation.
This is a feasibility trial registration with recruitment completed but no results posted; it measures feasibility and acceptability endpoints rather than clinical outcomes.
Mechanistic mouse model study demonstrating microbiome-mediated tryptophan metabolism disruption correlates with behavioral changes, but lacks human validation, quantified effect sizes, and comparative statistics necessary for clinical translation.
Retrospective cohort of 244 patients shows statistically significant improvements in infection control and reoperation rates favoring combination therapy, though observational design limits causal inference.