Advanced Solid Tumor

SEP 9, 2026 · PHASE 1/2 TRIAL

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

ClinicalTrials.gov

First-in-human Phase 1/2 study registration with no posted results; safety and dose-escalation design in early development stage.

AUG 19, 2026 · PHASE 1 TRIAL

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

ClinicalTrials.gov

This is a Phase 1 dose-escalation and dose-expansion trial registration with no results posted; it is a first-in-human safety and tolerability study designed to establish dosing, not efficacy.

AUG 14, 2026 · PHASE 1 TRIAL

An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors

ClinicalTrials.gov

Phase 1 trial in early-stage development assessing safety and preliminary antitumor activity; no results reported in this registry record.

AUG 11, 2026 · PHASE 1 TRIAL

M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors

ClinicalTrials.gov

First-in-human Phase 1 study with no results posted; designed to establish safety, tolerability, and recommended dose rather than to prove efficacy.

AUG 11, 2026 · PHASE 1 TRIAL

A Study of MGC026 in Participants With Advanced Solid Tumors

ClinicalTrials.gov

Phase 1 dose-escalation study of a novel biologic in early-stage development; no results are posted in this registry record, only planned study design and safety endpoints.

AUG 10, 2026 · PHASE 1/2 TRIAL

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

ClinicalTrials.gov

This is a first-in-human, phase 1/2 trial registration with no results posted; the study is actively recruiting and designed to establish safety, tolerability, and initial antitumor activity of a novel pan-KRAS inhibitor.

AUG 10, 2026 · PHASE 2 TRIAL

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

ClinicalTrials.gov

This is a Phase 2 proof-of-concept study registration with no results reported; the trial is actively recruiting and designed to explore HER3-DXd monotherapy across multiple solid tumor types.

AUG 10, 2026 · PHASE 1/2 TRIAL

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

ClinicalTrials.gov

This is an active clinical trial registry record with no reported results; Phase 1/2 design studying an investigational drug in a molecularly defined population with safety and dose-finding as primary objectives.