Disease

Advanced Cancer

3 developments in the corpus

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Latest

Everything in the corpus, newest first.

SEP 10, 2026 · PHASE 1 TRIAL

A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815

ClinicalTrials.gov

Phase 1 trial of a novel MAPK pathway inhibitor in advanced solid tumors; registry record with no results posted, only planned endpoints for safety, dosing, and antitumor activity assessment.

PreliminaryAdvanced Cancer NCT05557045 Jazz Pharmaceuticals

Reported

Planned enrollment98

Study phasePhase 1

Primary outcome (Part A)Number of Participants With Dose-Limiting T…

AUG 12, 2026 · PHASE 2 TRIAL

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

ClinicalTrials.gov

This is an active Phase 2 trial registration with no results yet posted; it describes a planned study of feasibility and safety in a small cohort.

PreliminaryAdvanced Cancer NCT06200155 Depression, Anxiety

Reported

Estimated enrollment30

PhasePhase 2

Primary outcome measureSafety and adverse events through study com…

AUG 11, 2026 · PHASE 1 TRIAL

A Study of MGC026 in Participants With Advanced Solid Tumors

ClinicalTrials.gov

Phase 1 dose-escalation study of a novel biologic in early-stage development; no results are posted in this registry record, only planned study design and safety endpoints.

PreliminaryAdvanced Cancer NCT06242470 MacroGenics

Reported

Planned sample size250

PhasePhase 1

Primary outcome measureNumber of participants with adverse events,…