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Nandu Thalange

Genesis HealthCare

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AUG 11, 2026 · JOURNAL ARTICLE

Optimal timing of recombinant growth hormone therapy in Prader-Willi syndrome: the case for very early initiation

Frontiers in Endocrinology

This is a narrative commentary synthesizing existing evidence to recommend early rhGH initiation in PWS, not reporting new primary data or a systematic review with meta-analysis.

Expert GuidanceGenetic and Kidney Cyst Diseases Genetic Syndromes and Imprinting Hussain Alsaffar

Reported

Mean height gain with rhGH+1.67 SDS

BMI z-score reduction with rhGH−0.67 SDS

Fat mass proportion decrease with…−6.5% SDS

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