JUL 17, 2026 · JOURNAL ARTICLE
Understanding antidepressant change patterns in the UK Biobank
The British Journal of Psychiatry
Large observational study from medical records with genetic association analyses, but lacks prospective design, randomization, and hard clinical outcomes; findings are descriptive and hypothesis-generating rather than confirmatory of treatment efficacy.
Reported
Recurrent depression – early disc…1.96
Recurrent depression – late disco…2.63
Anxiety – early discontinuation (…1.37