Alzheimer's Disease

SEP 9, 2026 · PHASE 1 TRIAL

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer's Disease (eAD)

ClinicalTrials.gov

This is a Phase 1 clinical trial registry record with no results posted; it describes planned safety and tolerability assessment in a small early-stage cohort.

SEP 9, 2026 · PHASE 2/3 TRIAL

Piromelatine 20 mg in Participants With Mild Dementia Due to Alzheimer's Disease

ClinicalTrials.gov

A terminated Phase 2/3 RCT with no results posted; the registry record documents planned design and enrollment only, without outcome data or efficacy findings.

SEP 8, 2026 · INTERVENTIONAL STUDY

Electroconvulsive Therapy for Treatment of Alzheimer´s Disease

ClinicalTrials.gov

This is a pilot study registration with no results posted; it is designed to test a novel hypothesis about ECT in Alzheimer's disease, too early to provide clinical evidence of efficacy.

SEP 4, 2026 · OBSERVATIONAL STUDY

Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)

ClinicalTrials.gov

This is a recruiting observational cohort study with no results posted; it is an early-phase data collection effort designed to characterize tau PET patterns and their relationship to clinical phenotypes in cognitive impairment.

SEP 4, 2026 · JOURNAL ARTICLE

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease.

International Journal of Molecular Medicine

In vitro mechanistic study using cell co-culture models to explore MALT1 inhibition as a potential AD target; no animal or clinical validation provided.

AUG 20, 2026 · PHASE 3 TRIAL

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

ClinicalTrials.gov

This is a Phase 3 trial registration with no posted results; the study is actively recruiting and outcomes have not yet been reported.

AUG 20, 2026 · INTERVENTIONAL STUDY

Central Auditory Processing Modulation Underlying Anxiety Reduction Using Clinically Designed Improvisatory Music

ClinicalTrials.gov

This is a registered trial protocol with no results reported; it is a pilot study designed to assess feasibility and generate hypothesis about a music intervention in Alzheimer's disease with anxiety.

AUG 17, 2026 · PHASE 1 TRIAL

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

ClinicalTrials.gov

This is a Phase 1 interventional registry record with no results posted; it describes a planned imaging study to measure cyclooxygenase elevation in neurodegenerative disease versus controls, but enrollment is ongoing and no outcomes have been reported.