SEP 4, 2026 · JOURNAL ARTICLE
Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease.
International Journal of Molecular Medicine
In vitro mechanistic study using cell co-culture models to explore MALT1 inhibition as a potential AD target; no animal or clinical validation provided.
Study details
DesignIn vitro co-culture cell study
InterventionMALT1 inhibitor 2 (MI-2) treatment to suppr…
ComparatorControl conditions without MI-2; NF-κB acti…