Acute Kidney Injury

SEP 10, 2026 · OBSERVATIONAL STUDY

Immune Evaluation for Postoperative Sepsis-AKI

ClinicalTrials.gov

This is a registry record describing a planned observational cohort study with no reported results; enrollment is ongoing and the study aims to develop biomarkers and phenotyping systems rather than test a defined intervention.

SEP 8, 2026 · INTERVENTIONAL STUDY

Early Endotoxin Burden Reduction With oXiris in Septic Shock Patients Requiring CRRT

ClinicalTrials.gov

This is a single-center, uncontrolled pilot study with no comparator group and an estimated enrollment of only 13 participants, designed to assess feasibility and biological effect on a surrogate endpoint (endotoxin level) rather than clinical outcomes.

SEP 2, 2026 · PHASE 2 TRIAL

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

ClinicalTrials.gov

Phase 2 interventional trial in a serious acute condition with surrogate renal endpoint; results not yet reported in this registry record.

AUG 26, 2026 · JOURNAL ARTICLE

Shrunken pore syndrome increased the risk of acute kidney injury after cardiac surgery: a cohort study.

Annals of Medicine

Retrospective cohort study in a single centre showing a statistically significant association between shrunken pore syndrome and postoperative acute kidney injury after cardiac surgery, with adequate sample size and sensitivity analysis, but limited by observational design and lack of prospective validation.

AUG 18, 2026 · PHASE 4 TRIAL

The Vancomycin Piperacillin/Tazobactam (VPT) Patient Safety Trial (VPS)

ClinicalTrials.gov

This is a recruiting Phase 4 interventional trial with no results posted; the registry record describes only the planned design and safety endpoints, not outcomes.

JUL 31, 2026 · JOURNAL ARTICLE

Safety and outcomes of dapagliflozin initiation in critically ill patients with acute kidney injury: A post-hoc analysis of the defender trial.

Journal of Critical Care

A post-hoc analysis from a controlled trial showing no safety signal for dapagliflozin in critically ill AKI patients, with near-neutral effects and physiological stability, but underpowered to detect clinically meaningful benefit or harm.

JUN 23, 2026 · OBSERVATIONAL STUDY WITH TARGET TRIAL EMULATION

Amino acid infusion and acute kidney injury after aortic surgery: a multicenter observational study with target trial emulation.

Renal Failure

Observational study with target trial emulation found no significant association between amino acid therapy and AKI, though hypothesis-generating subgroup signal in older patients.