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Sam Sebastian Smith

Institute of Cancer Research

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SEP 4, 2026 · JOURNAL ARTICLE

Oncofetal antigens as emerging targets in chimeric antigen receptor (CAR)-T cell-based immunotherapies: opportunities and challenges

Frontiers in Cell and Developmental Biology

A narrative mini-review synthesizing biological rationale, clinical trial experience, and emerging strategies for oncofetal antigen-targeted CAR-T therapies, offering expert perspective on opportunities and limitations rather than novel empirical findings.

Expert GuidanceAstero Klampatsa CAR-T Cell Therapy Research Sam Sebastian Smith

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