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A single-center prospective cohort study with a modest sample size demonstrating clinically meaningful metabolic improvements and weight loss after bariatric surgery in a specific population, but lacking a comparator arm and with trajectories identified post-hoc by unsupervised modeling.
This is a methodological development paper presenting a novel computational algorithm (SUDO) for modeling cellular dynamics from single-cell data, demonstrated on synthetic and real datasets but lacking clinical validation or peer review.
A proof-of-concept computational method for modelling liquid crystal configurations, demonstrated against limited comparators and without experimental validation beyond qualitative morphology matching.
This is an unrefereed arXiv preprint presenting a novel optimization algorithm with theoretical convergence analysis and empirical validation, but lacks peer review and clinical or applied evidence.