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Zhipeng Liu

Dalian Medical University

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AUG 14, 2026 · JOURNAL ARTICLE

Changing etiological spectrum and the rise of metabolic risk in liver cancer burden in China (1990–2021) with projections to 2036: a decomposition analysis based on the GBD 2021 study

BMC Cancer

Rigorous population-level analysis using GBD 2021 data with quantified trends, sex-stratified findings, and validated projection methodology, demonstrating a major epidemiological shift in liver cancer etiology in China with clear effect sizes and uncertainty intervals.

Strong EvidenceXin Wang Zhipeng Liu Liver Disease Diagnosis and Treatment

Reported

HBV ASPR trend (EAPC)−0.15

HBV ASPR EAPC 95% uncertainty int…−0.41 to −0.09

HCV ASPR trend (EAPC)−0.15

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