Researcher

Michael Starnbach

Harvard University

2 developments in the corpus

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JUL 28, 2026 · JOURNAL ARTICLE

Monitoring antigen-specific T cell responses to B. burgdorferi 2253490

The Journal of Immunology

Proof-of-concept study in a mouse model using engineered bacteria and adoptive T cell transfer, demonstrating that in vitro T cell reprogramming can reduce bacterial burden, but findings are not yet translatable to human Lyme disease prevention or treatment.

PreliminaryVector Borne Infectious Diseases Michael Starnbach Justin Brueggeman

Study details

DesignExperimental immunology study with adoptive…

InterventionEngineered B. burgdorferi expressing OVA ep…

ComparatorBb-control (non-OVA-expressing B. burgdorfe…

JUL 28, 2026 · JOURNAL ARTICLE

Chlamydia trachomatis serovar D induces Th17-mediated pathology 2257997

The Journal of Immunology

Mechanistic study in a murine model identifying serovar-specific immune polarization; raises questions about Th17-mediated pathology but does not yet establish clinical causation or inform therapeutic intervention.

Hypothesis-GeneratingIan Magill Michael Starnbach Andrea Lebron Figueroa

Study details

DesignComparative mechanistic study in murine gen…

InterventionGenital infection with C. trachomatis serov…

ComparatorGenital infection with C. trachomatis serov…