SEP 10, 2026 · JOURNAL ARTICLE
Comparison of live birth rates between calorie-restricted diet and metformin prior to ovulation induction therapy in women with polycystic ovary syndrome and overweight/obesity: a protocol for a multicenter, randomized comparative effectiveness trial
Frontiers in Public Health
This is a published protocol for an upcoming multicenter RCT; no results are presented, only the study design and rationale for a planned comparison of diet versus metformin in PCOS.
Reported
Intervention duration12 weeks
Randomization ratio1:1
Primary endpointLive birth rate