University at Buffalo, State University of New York
2 developments in the corpus
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Mechanistic screening study in a single clinical strain identifying phage resistance genes and antibiotic interactions, without clinical outcomes or in vivo validation to support practice change.
This is a mechanistic study using engineered nanomaterials and cell models to propose a novel repair pathway; it raises questions about stress granule exhaustion in infection rather than answering them with clinical or in vivo efficacy data.