AUG 5, 2026 · JOURNAL ARTICLE
Genome-wide transposon screening uncovers phage resistance mechanisms and bidirectional effects on antibiotic susceptibility in carbapenem-resistant Klebsiella pneumoniae
Antimicrobial Agents and Chemotherapy
Mechanistic screening study in a single clinical strain identifying phage resistance genes and antibiotic interactions, without clinical outcomes or in vivo validation to support practice change.
Reported
Bidirectional antibiotic suscepti…LPS deletions reduced antibiotic resistance…
Phage-antibiotic combinations tes…P545 + meropenem, P545 + colistin, P545 + c…