AUG 10, 2026 · JOURNAL ARTICLE
Integration of a multimeric STAT consensus site into the adenoviral genome to interfere with IFN signaling represents a novel concept to improve oncolytic virotherapy
Journal of Virology
Single-centre in vitro work in bladder cancer cells demonstrating a novel viral engineering concept with surrogate endpoints (replication, lysis, particle formation) but no clinical outcomes, animal models, or comparative efficacy data.
Study details
DesignIn vitro cellular study with viral construc…
InterventionXVir-N-14 (oncolytic adenovirus with multim…
ComparatorXVir-N-31 (parent oncolytic adenovirus with…