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Researcher

Wenmin Wang

Stanford University

1 development in the corpus

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SEP 9, 2026 · JOURNAL ARTICLE

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science

In vitro proof-of-concept in iPSC-derived cell models demonstrating feasibility of two gene therapy approaches, without in vivo efficacy, clinical outcomes, or animal validation.

PreliminaryWenmin Wang Yang Sun Retinal Development and Disorders

Study details

DesignIn vitro mechanistic proof-of-concept study

InterventionAAV2-OCRL gene augmentation therapy and pat…

ComparatorPatient-derived iPSC trabecular meshwork mo…

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