AUG 26, 2026 · JOURNAL ARTICLE
Safety and immunogenicity of an mRNA COVID-19 vaccine administered to adults: A phase 2, randomized, active-controlled trial.
Human Vaccines & Immunotherapeutics
Phase 2 randomized active-controlled trial in 425 vaccinated adults showing dose-dependent immunogenicity and acceptable safety profile for investigational mRNA vaccines comparable to licensed comparator, but requiring Phase 3 confirmation before clinical adoption.
Reported
Sample size425
Per-protocol immunogenicity analy…381
Randomization ratio1:1:1:1:1