JUL 22, 2026 · JOURNAL ARTICLE
Early treatment of acute anterior wall stemi with colchicine preserves the left ventricular ejection fraction
Aposta
Randomized controlled trial showing statistically significant improvement in LVEF and reduced myocardial injury markers with early colchicine in acute anterior-wall STEMI, but limited by single-centre design, short follow-up, and lack of hard clinical endpoints.
Reported
Primary endpoint: mean LVEF at 30…50.4 ± 6.1%
Primary endpoint: mean LVEF at 30…46.2 ± 6.4%
p-value for LVEF differencep<0.001