AUG 14, 2026 · JOURNAL ARTICLE
Decitabine Reprograms Temozolomide-Resistant Glioblastoma Through Epigenetic Reactivation and Mesenchymal Attenuation: A Multi-Omics Study
Cancers
Multi-omics mechanistic study in repositioned datasets with an exploratory prognostic model that fails external validation (C-index 0.55), generating hypotheses for combination therapy rather than providing actionable clinical evidence.
Reported
Differentially expressed genes pe…1114–1882
Direct epigenetic targets reactiv…146
Genes in genome-wide reversal ana…11,707