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Jinzhe Bi

Guilin Medical University

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AUG 14, 2026 · JOURNAL ARTICLE

Aptamer-functionalized exosomes co-delivering miR-934 inhibitor and gemcitabine for targeted pancreatic cancer therapy

Journal of Biological Engineering

Preclinical in vitro and in vivo work demonstrating proof-of-concept for a novel engineered exosome delivery platform; lacks human clinical data, phase trials, or controlled comparator arms with reported effect sizes and statistical significance.

PreliminaryJinzhe Bi Extracellular Vesicles in Disease Zhiyuan Jian

Study details

DesignPreclinical in vitro and in vivo study

InterventionAS1411-functionalized exosomes co-deliverin…

ComparatorFree gemcitabine and non-functionalized exo…

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