Retrospective cross-sectional study from a single centre describing prevalence patterns and associations in a resource-limited setting, without intervention or causal inference, requiring confirmation in prospective or comparative designs.
A single case report with detailed pathological and clinical description; illustrative of aggressive TNBC phenotype and CNS dissemination pattern, but no comparative data, outcome measure, or generalizable evidence.
A systematic review and meta-analysis of six controlled trials showing no statistically significant effect of Modified Atkins Diet on adipokine markers, confirming the absence of a robust metabolic benefit in this population.