Background Cardiovascular diseases (CVD) are the leading cause of death worldwide, and their epidemiology is correlated with genetic predisposition and exposure to risk. Brazil is
Background Organs from donors with positive blood cultures (BCx) have been shown to increase the risk of donor-derived infections. However, the percentage of BCx positivity in dono
A narrative review synthesizing scattered epidemiologic data on RHD in Latin America, lacking a systematic methodology, meta-analysis, or new primary data to support quantitative claims beyond citation of existing estimates.
Large population-based retrospective administrative study with robust sample size and clear epidemiologic findings, but uses diagnostic coding and medication dispensation as case identification without clinical validation, limiting causal inference and generalizability beyond Brazil's public system.
This is an expert perspective piece articulating clinical and public health principles about diagnostic stewardship and antimicrobial resistance, not reporting new empirical evidence.