Materials Today Bio

SEP 1, 2026 · JOURNAL ARTICLE

A Transdermal CRISPR/Cas9 Strategy Using Biodegradable Microneedles to Target YB-1 in Melanoma

Materials Today Bio

Early-stage preclinical work demonstrating proof-of-concept in cell and animal models; no human data, surrogate endpoints only, and no direct clinical comparator.

AUG 25, 2026 · JOURNAL ARTICLE

Advances in DNA nanostructures for pathogenic microorganisms

Materials Today Bio

This is a narrative review article presenting conceptual advantages and potential applications of DNA nanostructures against pathogens, with no primary empirical data, effect sizes, or clinical outcomes reported.

AUG 18, 2026 · JOURNAL ARTICLE

Bio-adhesive cationic carbon dots enable photodynamic reactive oxygen species generation for cariogenic biofilm suppression

Materials Today Bio

Sound preclinical study with in vitro biofilm efficacy and in vivo proof-of-concept in a rat caries model, but limited to animal data and lacks human clinical validation.

AUG 1, 2026 · JOURNAL ARTICLE

Targeted delivery of peptidoglycan hydrolases (PGH) via engineered extracellular vesicles (EVs) to clear intracellular bacterial infections

Materials Today Bio

Proof-of-concept study in cell culture and larval models demonstrating engineered EV-mediated delivery of a peptidoglycan hydrolase; lacks mammalian efficacy data, toxicity assessment, and clinical translation pathway.