Journal of the Egyptian National Cancer Institute

OCT 22, 2026 · JOURNAL ARTICLE

Outcomes of non-metastatic HER-2 positive breast cancer before and after the introduction of anti-HER-2 therapy: a retrospective study from a tertiary Egyptian center

Journal of the Egyptian National Cancer Institute

Abstract Background HER-2 positive breast cancer accounts for 15–20% of cases and is associated with aggressive behavior and poor prognosis. Anti-HER-2 therapy, including trastuzum

OCT 17, 2026 · JOURNAL ARTICLE

Ferroptosis in cancer: molecular mechanisms, tumour microenvironment, therapeutic resistance, and clinical translation

Journal of the Egyptian National Cancer Institute

Abstract Ferroptosis is a distinct form of regulated cell death driven by iron-dependent lipid peroxidation and oxidative membrane damage, and it differs fundamentally from apoptos

OCT 16, 2026 · JOURNAL ARTICLE

Cancer nanomedicine and RNA/Lipid nanoparticle platforms in oncology: developmental evolution, translational barriers, and precision-therapy opportunities

Journal of the Egyptian National Cancer Institute

Abstract Nanomedicine has become an important translational platform in oncology by enabling altered pharmacokinetics, controlled exposure, reduced systemic toxicity, intracellular

SEP 21, 2026 · REVIEW

Male breast cancer in Arab populations: a systematic review of molecular, genetic, and clinicopathologic characteristics

Journal of the Egyptian National Cancer Institute

Abstract Background Male breast cancer (MBC) accounts for less than 1% of all breast cancer cases, yet its incidence is increasing worldwide. Research on MBC remains limited, parti

SEP 17, 2026 · JOURNAL ARTICLE

Epigallocatechin-3-Gallate, the green tea polyphenol suppresses expression of CD31 and VEGFR2 and enhances the chemotherapeutic potential of irinotecan in AOM/DSS model of colorectal cancer in mice

Journal of the Egyptian National Cancer Institute

Abstract Background Conventional chemotherapeutic treatment of colorectal cancer causes adverse effects such as severe diarrhoea, mucositis and hepatotoxicity. This study aimed to

SEP 4, 2026 · JOURNAL ARTICLE

Unlocking the potential of bacteriophage-based therapeutic gene delivery in hepatocellular carcinoma

Journal of the Egyptian National Cancer Institute

This is a narrative review synthesizing preclinical and mechanistic concepts about bacteriophage-mediated gene delivery in HCC, raising questions about therapeutic potential rather than reporting empirical trial results or definitive evidence.

JUL 15, 2026 · JOURNAL ARTICLE

Immune organoids for Africa: a roadmap for bridging the innovation gap in infectious diseases and cancer research

Journal of the Egyptian National Cancer Institute

A narrative review synthesizing evidence and expert consensus on implementing immune organoid technology in African research contexts, proposing a strategic roadmap aligned with continental health research priorities.