Journal of Endocrinology

OCT 7, 2026 · JOURNAL ARTICLE

A nuclear ERK–ATF5 axis coordinates mitochondrial metabolism and thermogenic gene expression in brown adipocytes

Journal of Endocrinology

Abstract Obesity and diabetes arise from disrupted energy homeostasis, underscoring the need to identify mechanisms that enhance energy expenditure. Brown adipose tissue dissipates

SEP 14, 2026 · JOURNAL ARTICLE

Estrogen insensitivity syndrome: the ‘Upside Down’ of ESR1 mutations

Journal of Endocrinology

The estrogen receptor α (ERα) is a central regulator of 17β-estradiol (E2)-dependent physiological processes in reproductive and non-reproductive tissues. Deregulation of ERα signa

SEP 8, 2026 · JOURNAL ARTICLE

Time-restricted feeding improved metabolic hormone levels and energy metabolism in high-fat diet-fed Leap2 -/- Mice

Journal of Endocrinology

A controlled animal study with multiple metabolic endpoints showing that time-restricted feeding improves hormone profiles and energy metabolism in a genetic knockout model, but lacks direct clinical translatability and relies on surrogate outcomes.

AUG 6, 2026 · JOURNAL ARTICLE

Attenuation of Diet-Induced Obesity and Impaired Glucose Homeostasis by IL-2/Anti-IL-2 Complex and Hyperbaric Oxygen

Journal of Endocrinology

Preclinical mechanistic study in mice demonstrating that IL-2/anti-IL-2 complex and hyperbaric oxygen expand Tregs and improve metabolic parameters; requires translation to human disease before clinical relevance can be assessed.