Frontiers in Cell and Developmental Biology

OCT 23, 2026 · JOURNAL ARTICLE

Cardiovascular–kidney–metabolic syndrome: novel molecular mechanism and glucagon-like peptide-1-targeting therapy

Frontiers in Cell and Developmental Biology

Cardiovascular–kidney–metabolic (CKM) syndrome represents a systemic disease continuum arising from the progressive and reciprocal interactions among metabolic dysfunction, kidney

OCT 20, 2026 · JOURNAL ARTICLE

From epidemiology to molecular pathology: current research status and future prospects on the role of toxic metal exposure in the development and progression of bladder cancer

Frontiers in Cell and Developmental Biology

Bladder cancer remains a prevalent and lethal urinary malignancy, characterized by high recurrence rates and persistently poor prognosis for muscle-invasive disease. This clinical

OCT 20, 2026 · JOURNAL ARTICLE

Mechanisms by which programmed cell death mediates immune evasion and antitumour immunity in oropharyngeal cancer

Frontiers in Cell and Developmental Biology

The development and treatment response of oropharyngeal squamous cell carcinoma (OPSCC) are jointly shaped by tumour cell-intrinsic features and the tumour immune microenvironment

OCT 19, 2026 · JOURNAL ARTICLE

MiR-145 reprogramming facilitates fibrotic trajectory in the tumor microenvironment

Frontiers in Cell and Developmental Biology

The fibrotic subtype of the tumor microenvironment characterized by epithelial-mesenchymal transition, fibrosis, angiogenesis and immune exclusion, predicts poor outcomes across di

OCT 16, 2026 · JOURNAL ARTICLE

Progress in research on the use of induced pluripotent stem cells in tumor prevention, therapy, and tumor modeling

Frontiers in Cell and Developmental Biology

Induced pluripotent stem cell technology holds great promise for cancer research and immunotherapy. iPSCs possess pluripotency and unlimited self-renewal capacity, enabling their d

OCT 15, 2026 · JOURNAL ARTICLE

Evaluating cytokine-based therapeutics in human 3D in vitro immune-containing assembloids

Frontiers in Cell and Developmental Biology

Introduction Cancer immunotherapies require accurate preclinical models that recapitulate the complex cellular interactions within the human tumor microenvironment. While patient-d

OCT 14, 2026 · JOURNAL ARTICLE

Cellular origins and evolutionary dynamics of plasma cfDNA in solid tumors: integrating germline, tumor-derived, and hematopoietic variation for MRD and treatment guidance

Frontiers in Cell and Developmental Biology

Plasma cell-free DNA (cfDNA) is a heterogeneous and rapidly changing biological pool derived from malignant cells, normal tissues, and hematopoietic cells. The abundance and molecu

OCT 14, 2026 · JOURNAL ARTICLE

Metabolic control of methylation landscapes in cancer growth and plasticity: targeting the epigenetic–metabolic axis with natural compounds and emerging therapies

Frontiers in Cell and Developmental Biology

Cancer cell plasticity enables tumor cells to dynamically transition between diverse phenotypic states, including epithelial–mesenchymal plasticity stemness, dormancy, lineage swit