Cardiovascular health is a key factor in human longevity, affecting not just lifespan but also the quality of aging. We synthesize evidence across four risk factor domains: genetic
Pulmonary embolism (PE) is increasingly recognized as an episode of care that extends well beyond hospital discharge. Current guidance is distributed across several documents: the
Background Non-muscle-invasive bladder cancer (NMIBC) is commonly managed with intravesical BCG, whereas pembrolizumab is reserved for selected BCG-unresponsive high-risk disease.
Heart failure (HF) exhibits distinctive event-and time-dependent patterns in incidence and progression dynamics. Over time, the heart first undergoes (mal)adaptive cellular, tissue
Background Fluoropyrimidine-based chemotherapy is associated with cardiovascular events in patients with colorectal cancer, yet validated tools for pre-treatment cardiovascular ris
Background This study synthesized published meta-analyses to assess the quality, bias, and strength of evidence regarding mortality risk factors in patients with atrial fibrillatio
Purpose Anthracycline-induced cardiotoxicity remains an important complication in patients with breast cancer receiving systemic therapy, and effective preventive strategies remain
Background Non-steroidal aromatase inhibitors (NSAIs) are a cornerstone of adjuvant endocrine therapy in postmenopausal women with hormone receptor-positive (HR+) breast cancer. Gi