Frontiers in Artificial Intelligence

OCT 20, 2026 · JOURNAL ARTICLE

Machine learning models integrating 2D and 3D intratumoral heterogeneity features from multi-sequence MRI: accurate prediction of perineural invasion in pancreatic ductal adenocarcinoma

Frontiers in Artificial Intelligence

Introduction Perineural invasion (PNI) occurs in the majority of pancreatic ductal adenocarcinoma (PDAC) cases and is strongly associated with local recurrence, neuropathic pain, a

SEP 10, 2026 · JOURNAL ARTICLE

System architecture and interactive LLM prompt framework for the integration of clinical and mitochondrial data in obesity: a software prototype and feasibility study

Frontiers in Artificial Intelligence

A feasibility study of a software prototype with no clinical validation, efficacy testing, or comparison to standard care; demonstrates technical proof-of-concept only.

AUG 11, 2026 · JOURNAL ARTICLE

Application of dimensionality reduction and clustering techniques for the analysis of Carrion's disease cases in the period 2000–2024

Frontiers in Artificial Intelligence

An exploratory machine learning analysis of surveillance data using unsupervised methods to identify epidemiological profiles; methodologically sound for its class but lacks clinical validation, prospective application, or outcome prediction.

JUL 15, 2026 · JOURNAL ARTICLE

Artificial intelligence in cardiology: implications for healthcare outcomes

Frontiers in Artificial Intelligence

An integrative review and expert position paper identifying gaps in AI/precision medicine implementation for diverse cardiovascular populations, calling for systemic restructuring before deployment rather than reporting new empirical evidence.