European Thyroid Journal

OCT 1, 2026 · JOURNAL ARTICLE

Association of TP53 Mutational Status and Survival in Anaplastic Thyroid Cancer Treated with Dabrafenib Plus Trametinib

European Thyroid Journal

Abstract Objective Anaplastic thyroid cancer (ATC) is an extremely aggressive tumour, with high mortality rates. Dabrafenib plus Trametinib (DT) has significantly impacted the surv

SEP 28, 2026 · JOURNAL ARTICLE

Clinical Outcomes of Pembrolizumab Combination Therapy in Heavily Pretreated PDTC and Anaplastic Thyroid Cancer

European Thyroid Journal

Abstract Background Poorly differentiated (PDTC) and anaplastic thyroid carcinoma (ATC) are rare, aggressive malignancies with limited treatment options. Although targeted therapie

SEP 9, 2026 · JOURNAL ARTICLE

TERT Reactivation in Thyroid Cancer: Mechanisms, Clinical Implications, and Therapeutic Opportunities

European Thyroid Journal

A narrative review synthesizing mechanistic understanding and clinical evidence on TERT mutations in thyroid cancer, with expert consensus on risk stratification and emerging therapeutic strategies, but not a primary data study.