Abstract Background Methotrexate is commonly used to treat dermatological and rheumatological diseases, but in rare cases it can cause severe and potentially fatal pulmonary toxici
Abstract Background This study addresses diagnostic limitations of conventional etiological tests (CETs) in pulmonary infections by evaluating clinical utility of pathogen-targeted
Prospective cohort study with moderate sample size (184 patients) showing MS prevalence and one-year mortality/exacerbation associations in COPD, but limited by single-centre design, lack of comparator arm, and reliance on observational follow-up rather than intervention.
A narrative review synthesizing mechanistic biology and case evidence that identifies a biologically plausible but clinically unproven hypothesis about VEGFR inhibition in hemoptysis, explicitly noting absence of controlled trials and the paradoxical risk of fatal hemorrhage.