Eclinicalmedicine

OCT 7, 2026 · JOURNAL ARTICLE

Adjuvant radiotherapy in FIGO stage III dMMR endometrial cancer: evidence and perspectives in the molecular era

Eclinicalmedicine

Current guidelines incorporate chemo-immunotherapy for stage III–IV mismatch repair–deficient (dMMR) endometrial cancer, but the evidence supporting omission of adjuvant radiothera

OCT 7, 2026 · JOURNAL ARTICLE

Safety and tolerability of elinzanetant: a pooled analysis from four randomized clinical trials

Eclinicalmedicine

Background Elinzanetant is a dual neurokinin (NK)-1 and NK-3 receptor antagonist approved for the treatment of moderate-to-severe vasomotor symptoms (VMS) associated with menopause

SEP 23, 2026 · JOURNAL ARTICLE

E7386 plus lenvatinib in patients with advanced endometrial cancer that progressed on platinum-based chemotherapy and an anti-PD-(L)1 immunotherapy: a single-arm, open-label, global phase 1b/2 dose-expansion cohort

Eclinicalmedicine

Background Novel therapies are needed for advanced endometrial cancer (aEC) that recurs after chemotherapy + immunotherapy. Lenvatinib has antitumour activity in patients with aEC

SEP 1, 2026 · JOURNAL ARTICLE

European society of cardiology congress 2026

Eclinicalmedicine

This is a congress summary describing attendance and themes, not a scientific study or clinical trial with measurable evidence for evaluation.

AUG 15, 2026 · JOURNAL ARTICLE

Obesity at antiretroviral therapy initiation and long-term risk of cardiovascular disease, cancer, or death in people with HIV in Italy: a prospective cohort study

Eclinicalmedicine

Prospective cohort study with adequate sample size and hard clinical outcomes (CVD, cancer, death), but unadjusted effect is attenuated to borderline significance after adjustment (aHR 1.28, 95% CI 0.98–1.67, p=0.073), limiting definitive causal inference.

JUL 31, 2026 · JOURNAL ARTICLE

Mechanics of pandemics

Eclinicalmedicine

This is a conceptual framework paper presenting ten proposed fundamental mechanisms of pandemic dynamics without empirical testing, primary data analysis, or validation against specific outbreak data.