Diseases of the Colon & Rectum

OCT 15, 2026 · JOURNAL ARTICLE

A Novel Quantitative Endoscopic Tumor Regression Grading System for Predicting Pathological Response Following Neoadjuvant Therapy in Rectal Cancer

Diseases of the Colon & Rectum

BACKGROUND: While pathological and magnetic resonance imaging-based tumor regression grading systems are widely utilized following neoadjuvant therapy for rectal cancer, existing e

SEP 23, 2026 · JOURNAL ARTICLE

Early-Onset Colorectal Cancer: Contemporary Management, Immunotherapy, and Organ Preservation

Diseases of the Colon & Rectum

A 36-year-old man with no family history of colorectal cancer or inflammatory bowel disease presented with a 3-month history of bright red blood per rectum and constipation. Anosco

AUG 14, 2026 · JOURNAL ARTICLE

SHORT- VERSUS LONG-COURSE RADIATION IN TOTAL NEOADJUVANT THERAPY FOR LOCALLY ADVANCED RECTAL CANCER: A PROPENSITY-MATCHED NATIONAL CANCER DATABASE ANALYSIS

Diseases of the Colon & Rectum

Retrospective propensity-matched cohort study showing no difference in overall survival between radiation regimens in total neoadjuvant therapy for rectal cancer, confirming equipoise between approaches already in clinical use.

AUG 12, 2026 · JOURNAL ARTICLE

Building Machine Learning Models Based on Oxidative Stress Index Score to Predict Survival of Locally Advanced Rectal Cancer Receiving Different Neoadjuvant Therapy Patterns

Diseases of the Colon & Rectum

A retrospective, single-center machine learning study shows superior prognostic stratification versus conventional staging in locally advanced rectal cancer, but lacks prospective validation and external multi-center confirmation needed to guide clinical practice.