Abstract Background Ki-67 is a cellular proliferation marker with an established prognostic role in several types of human tumors, whereas its prognostic significance in colorectal
Well-designed single-center concordance study with clear methodology and strong statistical agreement (κ=0.98) that validates interchangeability of two antibodies in routine practice, but does not establish new clinical utility or change diagnostic approach.
Single-centre retrospective study with moderate diagnostic accuracy (AUC ~0.61) on a surrogate imaging endpoint; model performance is modest and requires external validation before clinical use.