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3 developments in the corpus
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SEP 23, 2026 · JOURNAL ARTICLE
Circulation Research
BACKGROUND: Negative clinical trials foster therapeutic nihilism and public skepticism, especially if they follow optimistic preclinical results. One way to increase the likelihood
SEP 11, 2026 · JOURNAL ARTICLE
Circulation Research
Abstract Background With obesity as a risk factor for atherosclerotic disease, recent research suggests that adipose tissue in obese animal models and humans can generate endocrine
AUG 12, 2026 · JOURNAL ARTICLE
Circulation Research
Sound mechanistic and preclinical work demonstrating a novel ERRα activator protects against anthracycline cardiotoxicity in animal models with direct target engagement, but lacks clinical trial data in human patients.